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Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide
Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide
Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide
Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide

Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide

SKU: 1451522159

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Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamideBaricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1 JAK2 inhibitor with nanomolar potency against JAK1 (5. 9 nM) and JAK2 (5. 7 nM). INCB028050 inhibits intracellular signaling of multiple proinflammatory cytokines including IL 6 and IL 23 at concentrations <50 nM. INCB028050 was also effective in multiple murine models of arthritis, with no evidence of suppression of humoral immunity or adverse hematologic

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Description

Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide

Haemophilus influenzae

Chemical Name: N1-(2-((2-(2

ME0328 was used at 10 µM in vitro and cellular assays

2414909-94-5

Baricitinib phosphate Size:Solid 2 mg Chemical Name: (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamideBaricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1 JAK2 inhibitor with nanomolar potency against JAK1 (5. 9 nM) and JAK2 (5. 7 nM). INCB028050 inhibits intracellular signaling of multiple proinflammatory cytokines including IL 6 and IL 23 at concentrations <50 nM. INCB028050 was also effective in multiple murine models of arthritis, with no evidence of suppression of humoral immunity or adverse hematologic

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