Rb Polyclonal Antibody, 100ul[BT-AP07689] Diagnostic Probes & Oligos This gene encodes both smooth

This gene encodes both smooth muscle and nonmuscle isoforms

particularly in cells of the myeloid and B-lymphoid lineages

The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle

which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies

CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53

Rb Polyclonal Antibody, 100ul[BT-AP07689] Diagnostic Probes & Oligos This gene encodes both smoothRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.