FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use This gene is located in

This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome

resulting from unregulated expression of the growth factor

This protein is located in the endoplasmic reticulum| and has been shown to possess ubiquitin ligase activity

These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins

Site-specific binding also suggests that 53BP1 and 53BP2 are involved in p53-mediated tumor suppression

FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use This gene is located inThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.