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SAP18 Rabbit Polyclonal Antibody, 50ul Supplements it's perfect for those whoHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex which includes SIN3 SAP30 HDAC1 HDAC2 RbAp46 RbAp48 and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3 mediated transcriptional repression when tethered to the promoter. A
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